First up is One-Punch Man, a series that has some variation in every episode as well as none at all.
Tonari No Seki-kun
Tonari no Seki-kun has a pleasantly complex premise. A diligent student, Rumi Yokoi just wants to pay attention in class; Unfortunately for him.
Megalo Box
Megalo Box surprised many when it first released in 2018, and recently surprised even more with the confirmation of its upcoming second season.
Baccano
Baccano was many people's first introduction to how anime could tell more adult stories, while still including fun, fantasy, and hilarious characters.
Erased
Erased is one of those "going back in time to change the past" stories, similar to Back to the Future, but it's incredibly well done.
Senyu.
Once upon a time in a fantasy world, a hero defeated the Demon King, sealing him for a thousand years.
No Game No Life
What if arguments were decided not with words or fists, but with the results of a game? This is the concept of No Game No Life, and it would have been fairly simple as a setting.
KonoSuba
Konosuba: God's Blessing on This Wonderful World, simply known as Konosuba, is the most popular comedic anime of this generation of all time, and for good reason.
Devilman Crybaby
Unlike many of the other series on this list, Devilman Crybaby is not a happy-go-lucky story or a comic piece.
Golden Boy
A classic anime comedy, Golden Boy is the poster boy for the perverted characters, Kintaro O.